Research in the Manning group follows two interconnected thrusts: Collective behavior in biological tissues and deformation in disordered solids. Click sub-topic headings below for additional detail.
Groups of cells exhibit interesting collective behavior that emerges from simple interactions between individual cells. We search for universal features and rules that govern this far-from-equilibrium behavior.
Geometric Signature Of Surface Tension In 3D Tissues
Manning group participants:
• Elizabeth Lawson-Keister
• Preeti Sahu
• Jennifer Schwarz (SU)
• Lisa Manning
Collaborators:
• Carien Niessen
• Matthias Rubsam
Simulating The Mechanical Coupling Between A Tumor And Its Extracellular Matrix Environment
Manning group participants:
• Tara Finnegan
• Amanda Parker
Collaborators:
• Jen Schwarz (SU)
• Lisa Manning (SU)
• Cristina Marchetti (UCSB)
Morphogen Gradients Inside Active Confluent Tissue
Manning group participants:
• Elizabeth Lawson Keister
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Organogenesis During Development
Manning group participants:
• Paula Sanematsu
• Gonca Erdemci-Tandogan
• Matthias Merkel
Collaborators:
• Jeff Amack (SUNY Upstate)
• Agnik Dasgupta (SUNY Upstate)
Mechanisms For Compartmentalization And Cell Sorting In Biological Tissues
Manning group participants:
• Daniel Sussman
• Preeti Sahu
Collaborators:
• Jen Schwarz (SU)
Rigidity In Confluent 3D Bulk Tissues And The Origin Of Rigidity In Vertex Models
Manning group participants:
• Matthias Merkel
• Daniel Sussman
Collaborators:
• Josef Käs, Andrea Liu and Tristan Sharp (U Penn)
Flocking And Pattern Formation In Confluent Tissues
Manning group participants:
• Michael Czajkowski
• Max Dapeng Bi
Collaborators:
• Matteo Paoluzzi (SU)
• Cristina Marchetti (SU)
• Fabio Giavazzi, Giorgio Scita, and Roberto Cerbino (Milano)
Looking for special rigid configurations of an underconstrained central-force network
Manning group participants: Tyler Hain
Collaborators: Chris Santangelo
If you push a pile of sand very lightly, it will respond elastically, but if you push beyond an extremely low threshold, it will begin to flow. But the system that it flows into will be qualitatively similar to the state it was just in. We are studying that marginal transition in low dimensional systems (2D and 3D):
Predicting Crowd Dynamics Using Local Structure
Manning group participants:
• Julia Giannini
• Ethan Stanifer
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Structural Evolution Of Amorphous Systems During Large Scale Deformation
Manning group participants:
• Ethan Stanifer
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Jammed Packings Under A Random Force
Manning group participants:
• Sudeshna Roy
• Ethan Stanifer
• Lisa Manning
Collaborators:
• Peter Morse
What Are The Distinct Mechanically Stable States In Jammed Solids?
Manning group participants:
• Peter Morse
• Sven Wijtmans
Collaborators:
• Martin Van Hecke
• Merlijn Van Deen (Leiden)
Modeling Jammed Solids with Sparse Random Matrices
Manning group participants:
• Ethan Stanifer
• Peter Morse
Collaborators:
• Alan Middleton (SU Physics)
Identifying Low-Frequency Excitations In Jammed Systems
Manning group participants:
• Ethan Stanifer
• Peter Morse
• Sven Wijtmans
Collaborators:
• Alan Middleton (SU Physics)
• Eric Corwin (U Oregon)
How can we predict rearrangements in non-Hamiltonian active disordered solids?
Manning group participants: Tyler Hain
Collaborators: Edan Lerner